International Journal on Magnetic Particle Imaging IJMPI
Vol. 12 No. 1 Suppl 1 (2026): Int J Mag Part Imag
https://doi.org/10.18416/IJMPI.2026.2603026

Proceedings Articles, ID 1022

Influence of System Matrix Concentration and Frequency Selection on Reconstructed MPI Signals

Main Article Content

Sathurya Jegatheeswaran (Institute of Medical Engineering, University of Lübeck, Lübeck, Germany), Hanna Meenen (Institute of Medical Engineering, University of Lübeck, Lübeck, Germany), Ksenija Gräfe (Institute of Medical Engineering, University of Lübeck, Lübeck, Germany), Thorsten M. Buzug (1) Institute of Medical Engineering, University of Lübeck, Lübeck, Germany; 2) Fraunhofer IMTE, Research Institution for Individualized and Cell-Based Medical Engineering, Lübeck, Germany)

Copyright (c) 2026 Sathurya Jegatheeswaran, Hanna Meenen, Ksenija Gräfe, Thorsten M. Buzug

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

In Magnetic Particle Imaging (MPI), the system matrix (SM) characterizes the spatial encoding properties of
the imaging system and the magnetic nanoparticle response. Ideally, for linear particle magnetization behavior,
the concentration at which the SM is measured should not affect the reconstructed image. In this study, two
SMs recorded with tracer concentrations of 8.5 mg(Fe)/ml and 1.92 mg(Fe)/ml were investigated. We show
that, although the same SM is used, reconstruction discrepancies occur when the frequency coverage differs.
We therefore propose to determine the usable frequency components based on the lower concentration SM to
ensure a consistent reconstruction basis.

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