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To avoid the disadvantages of classical batch-wise coprecipitation in the synthesis of iron oxide nanoparticles we developed a microfluidic synthesis platform with continuous flow mode which enables a faster and more efficient adjustment of relevant parameters like pH-value, temperature and educt concentration. Initial results of the electrostatically stabilized particles demonstrate the high potential for the use as tracer in magnetic particle imaging or contrast agent in magnetic resonance imaging outperforming the efficacy of the current gold-standard Resovist®.
Int. J. Mag. Part. Imag. 6(2), Suppl. 1, 2020, Article ID: 2009007, DOI: 10.18416/IJMPI.2020.2009007