International Journal on Magnetic Particle Imaging IJMPI
Vol. 12 No. 1 Suppl 1 (2026): Int J Mag Part Imag
https://doi.org/10.18416/IJMPI.2026.2603004

Proceedings Articles, ID 1003

Comparison of human-scale MPI system concepts using a 3D arbitrary-waveform magnetic particle spectrometer

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Justin Ackers (Fraunhofer-Einrichtung für Individualisierte und Zellbasierte Medizintechnik IMTE), Niklas Hackelberg (1) Fraunhofer IMTE, Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering, Lübeck, Germany; 2) Institute for Biomedical Imaging, Hamburg University of Technology, Hamburg, Germany), Tobias Knopp (1) Fraunhofer IMTE, Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering, Lübeck, Germany; 2) Institute for Biomedical Imaging, Hamburg University of Technology, Hamburg, Germany; 3) Section for Biomedical Imaging, University Medical Center Hamburg-Eppendorf, Hamburg, Germany), Matthias Graeser (1) Fraunhofer IMTE, Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering, Lübeck, Germany; 2) Chair of Metrology, Universität Rostock, Rostock, Germany)

Copyright (c) 2026 Justin Ackers, Niklas Hackelberg, Tobias Knopp, Matthias Graeser

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

In the field of Magnetic Particle Imaging (MPI) hybrid methods are utilizing the simplicity and high SNR of magnetic particle spectrometers to complement the imaging aspect by characterizing particles and measuring system matrices for fast system calibration. In this contribution we utilized the flexibility of our 3D arbitrary-waveform magnetic particle spectrometer to measure the system functions of three MPI scanner concepts inspired by clinical-scale head-sized MPI systems. Using these system matrices we are able the compare reconstructed images under the same noise, particle and reconstruction conditions gathering first qualitative insights into the imaging properties of the different scanners.

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