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Copyright (c) 2022 Anna C. Bakenecker, Anselm von Gladiss, Hannes Schwenke, André Behrends, Thomas Friedrich, Kerstin Lüdtke-Buzug, Alexander Neumann, Joerg Barkhausen, Franz Wegner, Thorsten Buzug
This work is licensed under a Creative Commons Attribution 4.0 International License.
The steering of microrobots by using magnetic fields offers applications for minimally invasive surgery or for establishing drug delivery scenarios. On the one hand, magnetic particle imaging (MPI) offers a tomographic, real-time visualization of the used magnetic microrobots. On the other hand, an MPI scanner can apply magnetic fields, which a microrobot can be steered with. Hence, MPI is of great interest for realizing the tracking and navigation of microrobots. Here, we show that a microrobot, which has been coated with superparamagnetic iron oxide nanoparticles (SPIONs) can be steered through a patient specific phantom of the middle cerebral artery into an aneurysm, where it should occlude the aneurysm and can be potentially used for a triggered drug release or a hyperthermia treatment. The acquired MPI images show that a tracking accuracy of 0.68 mm is achieved.