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Copyright (c) 2022 Klaus Natorf Quelhas, Mark-Alexander Henn, Thinh Q. Bui, Hunter R. Wages, Weston L. Tew, Solomon I. Woods
This work is licensed under a Creative Commons Attribution 4.0 International License.
Modeling of Magnetic Particle Imaging (MPI) systems allows for developing and testing novel methods for image reconstruction and simulating various setups without the need of real-life measurement data. Here we describe the the initial development of a C++ simulation software designed to provide more realistic MPI simulation data, by accounting for effects like non-linear gradient fields, non-uniform drive fields, space-dependent coil sensitivity, temperature gradients and particle relaxation, as well as the results of the comparison of the simulated signals against real-life Magnetic Particle Spectroscopy (MPS) measurements. In addition to MPI, the software is also suitable for simulating other applications, e.g. MPS, AC susceptibility and pulsed relaxometry measurements.
T. Knopp, N. Gdaniec, and M. Möddel. Magnetic Particle Imaging: from Proof of Principle to Preclinical Applications. Physics in Medicine & Biology, 62:R124–R178, 2017, doi:https://doi.org/10.1088/1361-6560/aa6c99.
M.-A. Henn, K. N. Quelhas, T. Q. Bui, and S. I. Woods. Improving model-based mpi image reconstructions: Baseline recovery, receive coil sensitivity, relaxation and uncertainty estimation. International Journal on Magnetic Particle Imaging, submitted for publication.
N. Derby and S. Olbert. Cylindrical magnets and ideal solenoids. American Journal of Physics, 78,(229):229–235, 2009, doi:https://doi.org/10.1119/1.3256157.
J. M. Camacho and V. Sosa. Alternative method to calculate the magnetic field of permanent magnets with azimuthal symmetry. Revista Mexicana de Física E, 59:8–17, 2013.
T. Knopp and T. M. Buzug, Magnetic Particle Imaging: An Introduction to Imaging Principles and Scanner Instrumentation. Berlin/Heidelberg: Springer, 2012, doi:10.1007/978-3-642-04199-0.
T. Q. Bui, W. L. Tew, and S. I. Woods. AC Magnetometry with Active Stabilization and Harmonic Suppression for Magnetic Nanoparticle Spectroscopy and Thermometry. Journal of Applied Physics, 128:224901, 2020, doi:https://doi.org/10.1063/5.0031451.