International Journal on Magnetic Particle Imaging IJMPI
Vol 9 No 1 Suppl 1 (2023): Int J Mag Part Imag
Safe and Rapid 3D Imaging: Upgrade of a Human-Sized Brain MPI System
Main Article Content
This work is licensed under a Creative Commons Attribution 4.0 International License.
Magnetic Particle Imaging hardware has reached human scale and thus patient safety questions and clinical application scenarios are in the focus of current research. In this work, we present a safe real-time 3D MPI systemfor cerebral applications. High voltages are avoided to ensure patient safety by a low voltage-high current transmit coil design. The developed 2D drive-field generator generates a field-free-point trajectory in the sagittal xz-planethat is shifted by a dynamic selection-field sequence along the y-axis. The scanner generates 3D images with 4 frames/second and allows for direct visualization of the clinically preferred transversal yz-plane, which is crucialfor future brain examinations. Advanced reconstruction techniques reach a system sensitivity of 4 μgFe with respect to the iron mass in a sensitivity study.