A synthesis apparatus for the continuous flow synthesis of Magnetic Nanoparticles

Abstract

In magnetic particle imaging, superparamagnetic iron oxide nanoparticles are used as a tracer material. By utilizing the non-linear magnetization of the particles, their concentration in the body can be determined with high spatial and temporal resolution. Some of the important properties of the particles are their core diameter, hydrodynamic diameter, size distribution, and magnetic properties. In order to be able to produce particles with adequate quality and high reproducibility, a prototype of a continuous-flow synthesis apparatus is designed and tested. This research deals with the design and construction of a device that can use the co-precipitation synthesis method to synthesis particles in continuous flow.