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Copyright (c) 2022 Oliver Buchholz, Sébastien Bär, Kulthisa Sajjamark, Jorge Chacon-Caldera, Jochen Franke, Ulrich G. Hofman
This work is licensed under a Creative Commons Attribution 4.0 International License.
The separation of signals based on particle type, their environment or temperature has added a useful layer to the foundation of spatial MP imaging. The multi-color approach of signal reconstruction offers a far-reaching option for clinical interventions such as the controllable and precise application of hyperthermia. In this study, a multi-color reconstruction approach was applied to highlight the potential of MPI for temperature monitoring. For this purpose, we heated a solution of SPIO nanoparticles with a high-power laser and reconstructed the corresponding dynamic temperature maps by MPI data acquisition. A good temporal and spatial correlation between the MPI-based temperature maps and fiber optic thermometer measurements was observed.