International Journal on Magnetic Particle Imaging IJMPI
Vol. 12 No. 1 Suppl 1 (2026): Int J Mag Part Imag
https://doi.org/10.18416/IJMPI.2026.2603023

Proceedings Articles, ID 941

Oxygen vacancy-regulated iron oxide nanoparticles for magnetic particle imaging

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Qian Liang (Beihang University), Yuling Bai (School of Engineering Medicine and School of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, China), Zhenqi Jiang (School of Medical Technology, Beijing Institute of Technology, Beijing, 100081, China), Jie Tian (School of Engineering Medicine and School of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, China), Yang Du (CAS Key Laboratory of Molecular Imaging, Institute of Automation, Chinese Academy of Sciences, Beijing, 100190, China)

Copyright (c) 2026 Qian Liang, Yuling Bai, Zhenqi Jiang, Jie Tian, Yang Du

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Magnetic particle imaging (MPI) is an emerging medical imaging technique with the advantages of high sensitivity, linear quantitation, and no ionizing radiation. The magnetic nanoparticles play a vital role in MPI. Hence, we investigated the effects of oxygen vacancies in iron oxide nanoparticles (IONPs) on MPI imaging performance. We developed IONPs with different oxygen vacancies and the results showed that as the oxygen vacancies of IONPs increased, the MPI signal initially increased and then decreased. And IONPs with two oxygen vacancies exhibited the optimal MPI imaging performance, which providing effective evidence for designing high-performance IONPs.

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