International Journal on Magnetic Particle Imaging IJMPI
Vol. 12 No. 1 Suppl 1 (2026): Int J Mag Part Imag
https://doi.org/10.18416/IJMPI.2026.2603003

Proceedings Articles, ID 973

Investigation of impact of tuning coil loading on particle signal harmonics in multi-frequency MPI

Main Article Content

Harald Radermacher (1 Institute of Imaging and Computer Vision, RWTH Aachen University, Aachen, Germany), Magdalena Kunz (1 Institute of Imaging and Computer Vision, RWTH Aachen University, Aachen, Germany), Franziska Schrank (1) 1 Institute of Imaging and Computer Vision, RWTH Aachen University, Aachen, Germany; 2) 2 Institute for Experimental Molecular Imaging, RWTH Aachen University, Aachen, Germany), Dennis Pantke (2) Institute of Imaging and ComputerInstitute for Experimental Molecular Imaging, RWTH Aachen University, Aachen, Germany), Florian Mueller (Institute for Experimental Molecular Imaging, RWTH Aachen University, Aachen, Germany), Volkmar Schulz (1) Institute of Imaging and Computer Vision, RWTH Aachen University, Aachen, Germany; 2) Institute for Experimental Molecular Imaging, RWTH Aachen University, Aachen, Germany; 3) Fraunhofer Institute for Digital Medicine MEVIS, Aachen, Germany)

Copyright (c) 2026 Harald Radermacher, Magdalena Kunz, Franziska Schrank, Dennis Pantke, Florian Mueller, Volkmar Schulz

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

In Magnetic Particle Imaging (MPI), suppression of the excitation feedthrough into the receive chain helps towards acquiring the fundamental frequency response of the superparamagnetic iron oxide nanoparticle (SPIONs), which is beneficial for quantitative measurements. As one approach, particularly suited for multi-frequency MPI (mf-MPI), tuning coil loading (TCL) has been shown to effectively reduce the feedthrough at the fundamental frequency way below the levels achievable with e.g. gradiometer coil arrangements alone. In this work, the effect of TCL on higher frequency components is evaluated by capturing the harmonics of a real particle signal, acquired by measurements at different excitation frequencies. A comparison between gradiometer-only and combined gradiometer plus TCL operation is presented. It is shown that TCL does not negatively impact the harmonics, hence provides an effective feedthrough suppression while preserving the higher frequency performance.

Article Details

References

[1] Gleich, B. and J. Weizenecker (2005). “Tomographic imaging using the nonlinearresponse of magnetic particles”. In: Nature 435, pp. 1214–1217.
[2] H. Radermacher, F. Schrank, D. Pantke, F. Mueller, M. Peters, and V. Schulz, “Highly flexible gradiometer coil arrangement offering improved passive compensation for multi-frequency MPI,” International Journal on Magnetic Particle Imaging IJMPI, Vol 9 No 1 Suppl 1 (2023), doi:10.18416/IJMPI.2023.2303030.
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