International Journal on Magnetic Particle Imaging IJMPI
Vol. 12 No. 1 Suppl 1 (2026): Int J Mag Part Imag
https://doi.org/10.18416/IJMPI.2026.2605001

Proceedings Articles, ID 980

X-ray-induced magnetic particle acoustic imaging by magnetic field modulation

Main Article Content

Guang Jia (Xidian University), Junxiao Huang (School of Physics, Xidian University, Xi’an, Shaanxi, China), Tong Su (Institute of Optics and Precision Mechanics of CAS, Chinese Academy of Sciences, Xi'an, Shaanxi, China), Yong'an Liu (Institute of Optics and Precision Mechanics of CAS, Chinese Academy of Sciences, Xi'an, Shaanxi, China), Yun Li (Institute of Optics and Precision Mechanics of CAS, Chinese Academy of Sciences, Xi'an, Shaanxi, China), Guo Li (School of Automation, Xi'an University of Posts & Telecommunications, Xi'an, Shaanxi, China), Shaojie Tang (School of Automation, Xi'an University of Posts & Telecommunications, Xi'an, Shaanxi, China), Jia Luo (College of Chemistry and Materials Science, Northwest University, Xi’an, Shaanxi, China), Mingli Peng (College of Chemistry and Materials Science, Northwest University, Xi’an, Shaanxi, China), Wenhui Huang (Department of Radiology, The First Affiliated Hospital, Jinan University, Guangzhou, Guangdong, China), Shuixing Zhang (Department of Radiology, The First Affiliated Hospital, Jinan University, Guangzhou, Guangdong, China), Jie Tian (CAS Key Laboratory of Molecular Imaging, Institute of Automation, Chinese Academy of Sciences, Beijing, China), Hui Hui (CAS Key Laboratory of Molecular Imaging, Institute of Automation, Chinese Academy of Sciences, Beijing, China), Tanping Li (School of Physics, Xidian University, Xi’an, Shaanxi, China)

Copyright (c) 2026 Guang Jia, Junxiao Huang, Tong Su, Yong'an Liu, Yun Li, Guo Li, Shaojie Tang, Jia Luo, Mingli Peng, Wenhui Huang, Shuixing Zhang, Jie Tian, Hui Hui, Tanping Li

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

A magnetic field-modulated X-ray Induced Magnetic Particle Acoustic Imaging (xMPAI) technique is proposed in this
study, which combines an external static magnetic field with ultrashort pulsed X-ray excitation for targeted imaging of
magnetic nanoparticles (MNPs). Under the modulation of a controlled external magnetic field, MNPs exhibit enhanced
thermoacoustic response due to magnetic polarization. We evaluated the feasibility of this technique through designed
phantom experiments and observed a significant signal enhancement. By introducing a magnetic field modulation
mechanism, this method improves the in-vivo detection sensitivity of MNPs, providing a potential strategy for achieving
high-contrast and molecular imaging of biological tissues.

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