International Journal on Magnetic Particle Imaging IJMPI
Vol. 9 No. 1 Suppl 1 (2023): Int J Mag Part Imag

Short Abstracts

Effect of matrix compressibility and temperature on MPI signal intensity

Main Article Content

Marzieh Salimi (Johns Hopkins University), Stéphane Roux (Institut UTINAM, UMR 6213 CNRS-UFC, Université de Franche-Comté, Besançon, France), Jeff Bulte (The Russell H. Morgan Department of Radiology and Radiological Science, Division of MR Research and Cellular Imaging Section, Institute for Cell Engineering, the Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.)


A major advantage of MPI compared to other in vivo imaging modalities is a linear relationship between the label (SPIO) concentration and MPI signal. However, the MPI signal can be affected by intrinsic tissue matrix parameters, which are often not known a priori, presenting challenges for proper SPIO quantification in vivo. We report here on the effects of matrix compressibility and temperature on MPI signal in tissue-mimicking phantoms, which has direct relevance to MPI-guided magnetic fluid hyperthermia.


Article Details


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