Microwave-assisted high-speed synthesis of superparamagnetic iron-oxide nano¬particles

Abstract

In this work, the microwave-assisted synthesis of superparamagnetic iron oxide nanoparticles (SPIONs) for MPI is presented. Compared to conventional coprecipitation, microwave-assisted synthesis in specially designed microwave reactors enables good yields while reaction times can be reduced to a few minutes. To find the best synthesis route, various parameters such as the base used, reaction temperature, heating and cooling time were analysed. Various dextrans (molecular weight 10,000-100,000) were used to assess whether the methods can also be applied to other coating materials. The first results of this evaluation study are presented here.