International Journal on Magnetic Particle Imaging IJMPI
Vol. 12 No. 1 Suppl 1 (2026): Int J Mag Part Imag
https://doi.org/10.18416/IJMPI.2026.2603041
Proceedings Articles, ID 994
Domain-weighted Block Coordinate Descent for quantitative single-sided MPI reconstruction
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Copyright (c) 2026 Lingwen Hou, kaixiong Yang, Yihan Wang, Shouping Zhu
This work is licensed under a Creative Commons Attribution 4.0 International License.
Abstract
Single-sided Magnetic Particle Imaging (MPI) provides a solution suitable for intraoperative localization. However, asymmetric coil arrangements cause nonuniform magnetic fields and depth-dependent sensitivity decay, leading to biased reconstructions. This paper proposes a domain-weighted Block Coordinate Descent (DW-BCD) algorithm for quantitative single-sided MPI reconstruction. A preliminary reconstruction estimates the signal support domain, from which weighting and regional partitioning are derived. The subsequent reconstruction combines block-wise domain-weighted and global total variation(TV) regularization. Experiments show that DW-BCD effectively reduces depth-related concentration bias, enabling accurate quantitative reconstruction of magnetic nanoparticle distributions for clinical applications of single-sided MPI.
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References
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